Saturday 1 November 2014

Early childhood atopy and autism risk

De profundis clamo ad te, domine
Regular readers will probably have heard something like this before so I'm sorry if I'm repeating myself: "The presence of any atopic disease in early childhood increased the risk of developing ADHD [attention deficit hyperactivity disorder]... and ASD [autism spectrum disorder]... in later life".

So said Mu-Hong Chen and colleagues [1] with yet another 'big data' paper coming out of Taiwan.

There is little point in me turning this research into some sort of mega-post given that this topic has featured so heavily on this blog. In case you missed them, here are some of the relevant posts:

  • Allergic and autoimmune diseases and autism (2012) (see here)
  • Asthma increases risk of ADHD? (2013) (see here)
  • Asthma as a risk factor for autism? (2014) (see here)
  • Autism, ADHD and allergy: Taiwan and big data (again) (2014) (see here)

Lazy? Yes, I am being a bit lazy in this post by just supplying older links but what more can I say apart from that there seems to be a complicated relationship between immune function and behaviour. Oh, and other research from this group might also be worthwhile looking at as per studies linking epilepsy and atopic dermatitis [2] and major depression and/or bipolar disorder and asthma [3] knowing about the various comorbidity relationships with autism (see here and see here).

And here is some lazy music to accompany my lazy post...


[1] Chen MH. et al. Is atopy in early childhood a risk factor for ADHD and ASD? A longitudinal study. J Psychosom Res. 2014 Oct;77(4):316-21.

[2] Chen MH. et al. Risk of epilepsy among patients with atopic dermatitis: a nationwide longitudinal study. Epilepsia. 2014 Aug;55(8):1307-12.

[3] Chen MH. et al. Higher risk of developing major depression and bipolar disorder in later life among adolescents with asthma: a nationwide prospective study. J Psychiatr Res. 2014 Feb;49:25-30.

---------- Chen MH, Su TP, Chen YS, Hsu JW, Huang KL, Chang WH, Chen TJ, Pan TL, & Bai YM (2014). Is atopy in early childhood a risk factor for ADHD and ASD? A longitudinal study. Journal of psychosomatic research, 77 (4), 316-21 PMID: 25280829

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