tag:blogger.com,1999:blog-5548560205914833324.post2023392588661207057..comments2023-04-23T00:16:48.148+01:00Comments on Questioning Answers: Autism: the sum of its SNPs?Paul Whiteleyhttp://www.blogger.com/profile/14288851488012254897noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-5548560205914833324.post-11542612547981237712012-10-16T21:10:16.207+01:002012-10-16T21:10:16.207+01:00Many thanks for the comment Harold.
To add to you...Many thanks for the comment Harold.<br /><br />To add to your observations:<br /><br />(a) Diet and lots of other things have changed in the 50+ years you talk about. Singling out cholesterol, there are some pretty obvious changes to the dietary recommendations given worldwide, some of which were discussed in a recent TV series here in the UK called 'The Men Who Made Us Fat' <br />http://www.guardian.co.uk/business/2012/jun/11/why-our-food-is-making-us-fat<br />Although I don't want to make too many sweeping generalisations, there is a body of work looking at cholesterol in relation to autism: http://questioning-answers.blogspot.co.uk/2011/11/cholesterol-levels-in-autism-vader-or.html <br />It's still however a work in progress.<br /><br />(b) The possible reasons for de novo mutations appearing? Outside of parental age (focused quite a bit on paternal age it has to be said), one has to wonder whether there might be lots of different reasons. What we might call 'spontaneous' mutations now, will probably not be so named in years to come.Paul Whiteleyhttps://www.blogger.com/profile/14288851488012254897noreply@blogger.comtag:blogger.com,1999:blog-5548560205914833324.post-40228590474046174092012-10-16T20:43:18.320+01:002012-10-16T20:43:18.320+01:00I agree with Lorri on the social trends and practi...I agree with Lorri on the social trends and practices. This is clearly evident over the history of the developing increases in autism. Specifically my concern is the changing recommendations as regards a healthy diet. The recommendations from 1960 to present times has resulted in avoiding or limiting the foods that are high in the nutrients required for good brain health based upon the composition of healthy brain tissue. To eliminate the cholesterol containing foods is to significantly reduce or eliminate the vitamin choline, amino acids, fatty acids, minerals and other vitamins. Those with autism have been shown to be low or lacking at least fifty needed nutrients.<br /><br />I also agree that the concern for genetic causes is a bit of a ruse. There are numerous mutated genes but most appear only in the children rather than passed on from the parents. My question is what causes the change? I believe there is evidence that genetic changes result from a lack of specific needed nutrients rather than being the cause for autism in it's many forms. Apparently those that lose their symptoms when a proper diet is provided have also recovered normal genes. Harold Rongey, Ph.D.https://www.blogger.com/profile/11546678711462612777noreply@blogger.comtag:blogger.com,1999:blog-5548560205914833324.post-7194570664200617172012-10-16T19:27:20.843+01:002012-10-16T19:27:20.843+01:00Thanks Lorri.
I agree and please don't apolog...Thanks Lorri.<br /><br />I agree and please don't apologise for being picky. <br /><br />'Environment' covers lots of territory ranging from our chemical environment, to our social environment, even our environment in-utero, etc. <br /><br />In my defence on this post, I didn't really have the time or space to define environment or indeed go into the various factors pertinent to it. My point however is that we, as a people, seem to be a little too accepting of the whole 'genes are king' premise without perhaps paying enough attention as to how our genes are part of a wider relationship as per what seems to be emerging from the field of epigenetics.Paul Whiteleyhttps://www.blogger.com/profile/14288851488012254897noreply@blogger.comtag:blogger.com,1999:blog-5548560205914833324.post-19770470354789504222012-10-16T17:30:33.419+01:002012-10-16T17:30:33.419+01:00This might seem picky and has only to do with this...This might seem picky and has only to do with this blog in this question re environmental factors, but in this overall discussion in any venue it would be nice to have some demarcation of 'territory' when talking about environmental factors. For instance, toxins and pollutants are one set of elements, but so are social trends and practices, especially those that challenge acceptability of behaviors and/or alter formerly accepted courses of childhood development. Lorrihttps://www.blogger.com/profile/06251310750139178931noreply@blogger.comtag:blogger.com,1999:blog-5548560205914833324.post-87036400459294394972012-10-16T09:25:28.984+01:002012-10-16T09:25:28.984+01:00Thanks Harold. I agree.Thanks Harold. I agree.Paul Whiteleyhttps://www.blogger.com/profile/14288851488012254897noreply@blogger.comtag:blogger.com,1999:blog-5548560205914833324.post-7820846443045162352012-10-16T07:09:23.712+01:002012-10-16T07:09:23.712+01:00Q: "should we perhaps be looking at environme...Q: "should we perhaps be looking at environmental factors with as much assiduity as we do genetic ones?"<br /><br />A: Yes!Anonymoushttps://www.blogger.com/profile/05838571980003579163noreply@blogger.com